Welcome to DECIPHER
A clinical study for patients with gastrooesophageal cancer. Find out more on this website before registering your interest in participating.
ABOUT THE TRIAL
​DECIPHER is a clinical research study which is looking into how effective a new drug called trastuzamab deruxtecan (T-DXd) is at treating people with gastrooesophageal adenocarcinoma (cancer).
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If you have oesophageal cancer and are receiving chemotherapy prior to surgery, you may be eligible for this study.
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To find out more, have a look at our trial Infographic or have a read through the Stage 1 Screening Patient Information Sheet.​​
DECIPHER Infographic - What does participating in DECIPHER entail.
Where To Participate
There are currently 12 Hospitals recruiting to DECIPHER.
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Belfast ​Health and Social Care Trust
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Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust.
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University Hospitals Coventry & Warwickshire​ NHS Trust.
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Ninewells Hospital and Medical School Dundee.
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Guy's Hospital, Guys and St Thomas' NHS Foundation Trust.
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Castle Hill Hospital, Hull University Teaching Hospitals NHS Trust.
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Leeds General Infirmary, The Leeds Teaching Hospitals NHS Trust.
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John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust. ​
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Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust. ​
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University College London Hospitals NHS Foundation Trust. ​​​​
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The Christie NHS Foundation Trust (Manchester).​
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Derriford Hospital, University Hospital Plymouth NHS Trust.
Patients do NOT need to be currently treated at a DECIPHER hospital but will need to be referred to one for treatment.
Patient Information Video
Dr Lizzy Smyth, Chief Investigator of the DECIPHER trial, introduces the trial and explains what patients can expect if they decide to take part. This video should be watched in conjunction with reading the full Patient Information Sheet.
Get in touch
We welcome your enquires
+44 (0)23 8120 5154
Southampton Clinical Trials Unit,
MP131, Southampton General Hospital,
Tremona Road, Southampton,
SO16 6YD​​